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Amazon Malaria Initiative
AMI Countries

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Initially, AMI included Ecuador, Peru, Bolivia, Brazil, Colombia, Venezuela, Guyana, and Suriname. French Guiana participates in meetings, though it is not officially a member. Venezuela ceased participation at the end of 2007. Because these countries are in the Amazon Basin, they have found it advantageous to take a regional approach to combating malaria, emphasizing cooperative efforts in evaluating, for example, which antimalarial drugs are effective in the region.

Such efforts appear to have paid off. Between 2002 and 2006, Peru reduced laboratory-confirmed malaria cases by 30 percent. Brazil has achieved similarly dramatic results. From 77 malaria-related deaths in 2002, Brazil reached a zero-mortality level by 2005.

Such results reflect the fact that the AMI partner countries have instituted use of artemisinin-based combination therapy (ACT) for treating P. falciparum infections. This change occurred after efficacy studies established the inadequacy of previous treatment methods based primarily on chloroquine—a drug to which P. falciparum has, unfortunately, demonstrated extensive resistance in recent years.

One factor stalling the establishment of efficacious antimalarial treatments had been the lack of adequate surveillance techniques in the region. Through regional cooperation, this problem has been solved. Not only has surveillance been improved, but the effectiveness and accuracy of laboratory testing have improved thanks to support from AMI partners and a partner USAID program aimed at controlling antimicrobial resistance (the South American Infectious Disease Initiative, or SAIDI).

With improved quality assurance and quality control applied to antimalarial medications, as well as improved supply-chain management, treatment efforts have not only increased in efficacy, but have reduced the regional malaria burden significantly. Between 2001 and 2007, the number of reported cases of malaria declined by nearly 18% within the AMI partner countries. The number of malaria-associated deaths in the region declined by approximately 50 percent during the same period: from 252 to 127.

Bolivia
Bolivia is currently updating its Standard Treatment Guidelines (STGs) based on studies of currently available antimalarial drugs and their efficacy. Once the new standard treatments have been devised, medical personnel will be trained accordingly. Bolivia's Ministry of Health.
Brazil
Brazil is undertaking the task of standardizing practices for prescribing and dispensing antimalarials throughout the country. Currently, each state has its own standards for how medications are prescribed, dispensed, and taken by patients. Brazil's Ministry of Health.
Colombia
Colombia is encouraging its citizens to seek more immediate treatment for malaria symptoms throughout outreach activities. Studies carried out in Tierra Alta, Córdoba, in 2004; in Guapi, Cauca, in 2004; and in Apartadó, Antioquia, in 2005 revealed a low level of adherence to courses of treatment for uncomplicated malaria caused by Plasmodium vivax and P. falciparum, and that approximately 48 percent of the interviewed people suffering from malaria do not realize that treatment is free at public health centers. Colombia's Ministry of Health.
Ecuador
Ecuador is currently addressing issues with patient adherence to drug protocols, a problem identified by AMI studies conducted by MSH/SPS. Ecuador's Ministry of Health.
Guyana
Guyana has been faced with growing infestations of P. falciparum, despite an aggressive program of distributing bed nets. This situation is complicated by the growth of mining activity along the Brazilian border, where malaria is prevalent. The Ministry of Health is struggling to convince citizens to seek treatment at regional health facilities rather than self-medicating using questionable commercially available medications. Nevertheless, malarial infections in Guyana have declined over the past decade. Guyana's Ministry of Health.
Peru
Peru has been a leader in implementing artemisinin-based combination therapies (ACTs). Peru's Ministry of Health.
Suriname
Suriname information is pending. Suriname's Ministry of Health.
Stories from the Field
Strengthening prevention and control of malaria in Chocó, 2006 – 2009
blood

A microscopist takes a blood sample for malaria testing in Chocó, Colombia, 2009.

Piura Works to Improve Medicine Storage Conditions
warehouse

After the provision of technical support, the loading and unloading areas of the warehouse were protected from the weather and climate with a roof.

Collaborations between official medicines control laboratories
members of OMCL in photo together in front of building

OMCL representatives attended in September 2009 a sub-regional workshop organized by PQM and PAHO to discuss sustainable approaches for strengthening OMCLs at national and regional levels.

Clean, cool and collected: Better storage conditions for antimalarials in Ecuador
Clean, cool and collected: Better storage conditions for antimalarials in Ecuador

Storage of medicines and supplies before and after the intervention

Rethinking pharmaceutical management in low incidence settings
Clean, cool and collected: Better storage conditions for antimalarials in Ecuador

AMI partners, led by MSH, met in April 2010 to address medicine procurement in low incidence settings.


DISCLAIMER:The information provided on this Web site is not official U.S. Government information and does not represent the views or positions of the U.S. Agency for International Development or the U.S. Government.

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Last updated on: 5/23/2011